If you have the parent folder selected for backup, then all sub-folders will be backed up dynamically each time the backup runs.

Perhaps I did a poor job of explaining the issue, so let me try again. The Autodesk backup creates a new folder each scheduled backup, same files as the previous backup (approximately 30GB, same set of files, but FULL backup of each file, not incremental). So, my backup plan is copying 30GB daily to cloud storage, instead of only the block-level changes. I can handle this with a little file-level scripting, but thought there may be a better solution within the backup plan. Thanks.

Block-level only works within files. It doesn't matter if your files have the same names as those used in other folders. They are treated as new files and need to be backed up in full. Since they are unlikely to ever change, they'll never be backed up again. If you start deleting older backups, they will eventually be removed from storage, depending on your retention settings. What's your desired retention as it relates to the Autodesk backup files? If it differs from other files you're backing up, you could create a separate backup plan for Autodesk.